GlykoPrep™ N-Glycan Platform
Innovative GLYKO®-Technology Solutions powered by AssayMAP® technology and available only from ProZyme.
The distribution of N-linked glycans plays a critical role in the pharmacology of therapeutic proteins, potentially affecting immunogenicity, pharmacokinetics and pharmacodynamics. While prompt information is highly valuable, the manual, complex and multi-day sample preparation usually limits analysis to only the most critical decision points. The GlykoPrep N-Glycan Platform enables preparation of crude or purified bioprocess samples for full N-glycan analysis in 2-3 hours. Learn more from ProZyme.
- crude sample to analysis in 2-3 hours
- integrated mAb purification (optional)
- streamlined workflow
- manual to full-automation
- QC release, PAT and strain selection
snapshot protocol
recent posters
November 2011 — On the Path to Biobetter Therapeutic Glycoproteins: Simple and Rapid Domain-Specific Screening to Target and Control Optimal Glycan Profiles Steven W. Mast1, Bopha L. Sun1, Michael J. Kimzey1, Shiva Pourkaveh1, Abdel Minalla1, F. Ted Haxo1, Craig Nishida1, E. Jo Wegstein1, and Scott P. Fulton2 [1 ProZyme Inc. Hayward, CA, USA, 2 BioSystem Development, LLC, Madison WI, USA]
November 2011 — Improving Standard N-Glycan Sample Preparation with Manual Automation Using Microchromatography to Improve Efficiency, Accuracy, and Reproducibility Toni R. Hofhine, Gilson, Inc., 3000 Parmenter St., Middleton, WI, USA and E. Jo Wegstein and Craig H. Nishida, ProZyme, Hayward, CA, USA
November 2011 — A High-Throughput Platform for Preparation of APTS-Labeled N-Glycans: Improving the Accuracy, Reproducibility and Time-to-Results of N-Glycan Profiling Michael Kimzey1, Shiva Pourkaveh1, Steven Mast1, Bopha Sun1, Abdel Minalla1, Ted Haxo1, Craig Nishida1, Jo Wegstein1, Andras Guttman2,3, Akos Szekrenyes3, Zoltan Szabo2, Barry Karger2, Jeff Chapman4, Hans Dewald4 [1 ProZyme, Inc., Hayward, CA; 2 Barnett Institute, Boston, MA; 3 Horvath Laboratory of Bioseparation Sciences, Debrecen, Hungary; 4 Beckman Coulter, Inc., Brea, CA]
November 2011 — Rapid Sample Preparation of Biologics to Support High-throughput and High-resolution Glycan Analysis by Capillary Electrophoresis Andras Guttman1, Zoltan Szabo1, Barry Karger1, Jo Wegstein2, Craig Nishida2, Jeff Chapman3, Hans Dewald3, Stefan Mittermayr4, Jonathan Bones4, Margaret Doherty4, and Pauline Rudd4 [1 Barnett Institute, Boston, MA, USA; 2 ProZyme, Inc., Hayward, CA USA; 3 Beckman Coulter, Inc., Brea, CA USA; 4 National Institute for Bioprocessing Research and Training, Dublin, Ireland]
Contact us for a demonstration.