Resource Library
Guidebooks
AssayMAP Spin Format Technology — the basics, technology, AssayMAP cartridge, tips, tricks and more
Protocols
Protein A Cartridges Protocol — 30-minute spin-format protocol
Scientific Posters
November 2011 — On the Path to Biobetter Therapeutic Glycoproteins: Simple and Rapid Domain-Specific Screening to Target and Control Optimal Glycan Profiles Steven W. Mast1, Bopha L. Sun1, Michael J. Kimzey1, Shiva Pourkaveh1, Abdel Minalla1, F. Ted Haxo1, Craig Nishida1, E. Jo Wegstein1, and Scott P. Fulton2 [1 ProZyme Inc. Hayward, CA, USA, 2 BioSystem Development, LLC, Madison WI, USA]
November 2011 — Improving Standard N-Glycan Sample Preparation with Manual Automation Using Microchromatography to Improve Efficiency, Accuracy, and Reproducibility Toni R. Hofhine, Gilson, Inc., 3000 Parmenter St., Middleton, WI, USA and E. Jo Wegstein and Craig H. Nishida, ProZyme, Hayward, CA, USA
November 2011 — A High-Throughput Platform for Preparation of APTS-Labeled N-Glycans: Improving the Accuracy, Reproducibility and Time-to-Results of N-Glycan Profiling Michael Kimzey1, Shiva Pourkaveh1, Steven Mast1, Bopha Sun1, Abdel Minalla1, Ted Haxo1, Craig Nishida1, Jo Wegstein1, Andras Guttman2,3, Akos Szekrenyes3, Zoltan Szabo2, Barry Karger2, Jeff Chapman4, Hans Dewald4 [1 ProZyme, Inc., Hayward, CA; 2 Barnett Institute, Boston, MA; 3 Horvath Laboratory of Bioseparation Sciences, Debrecen, Hungary; 4 Beckman Coulter, Inc., Brea, CA]
November 2011 — Rapid Sample Preparation of Biologics to Support High-throughput and High-resolution Glycan Analysis by Capillary Electrophoresis Andras Guttman1, Zoltan Szabo1, Barry Karger1, Jo Wegstein2, Craig Nishida2, Jeff Chapman3, Hans Dewald3, Stefan Mittermayr4, Jonathan Bones4, Margaret Doherty4, and Pauline Rudd4 [1 Barnett Institute, Boston, MA, USA; 2 ProZyme, Inc., Hayward, CA USA; 3 Beckman Coulter, Inc., Brea, CA USA; 4 National Institute for Bioprocessing Research and Training, Dublin, Ireland]
October/November 2011 — Automated, High Precision, 30 Minute Immunoassays for Bioprocess Impurity Measurements and Rapid, Automated Sample Preparation for Peptide Mapping of Antibodies and Recombinant Proteins BioProcess International Conference & Exhibition (October 31–November 4, 2011) in Long Beach, CA
September 2011 — On the Path to Biobetter Therapeutic Glycoproteins: Simple and Rapid Domain-Specific Screening to Target and Control Optimal Glycan Profiles Steven W. Mast1, Bopha L. Sun1, Michael J. Kimzey1, Shiva Pourkaveh1, Abdel Minalla1, F. Ted Haxo1, Craig Nishida1, E. Jo Wegstein1, and Scott P. Fulton2 [1 ProZyme Inc. Hayward, CA, USA, 2 BioSystem Development, LLC, Madison WI, USA]
August 2011 — A New High Throughput Microchromatography System for Protein Sample Prep Proteomics Symposium: Proteomic Technologies & Applications to Human Disease (August 4–6), Madison, WI, Steve Murphy, Michael Bovee, Jennifer Reich, Zach Van Den Heuvel & Scott Fulton, BioSystem Development, LLC, Madison, WI USA
June 2011 — A New High Throughput Microchromatography System for Protein Sample Prep 59th ASMS Conference on Mass Spectrometry and Allied Topics, Denver, CO, Scott Fulton, Steve Murphy, Michael Bovee, Jennifer Reich, & Zach Van Den Heuvel, BioSystem Development, LLC, Madison, WI USA, N. Leigh Anderson, Plasma Proteome Institute, Rockville, MD USA
March 2011 — Evaluation of a cartridge-based technology for protein purification and immunoassays IBC Life Sciences: 26th International Antibody Development & Production, Bellevue, WA, Susan Flor, Martin Vanderlaan, Yun Tang, Kevin Lin and William Waite, Analytical Operations, Pharma Technical Development, Genentech, Inc.
March 2011 — A Novel, High-Throughput Method for the Measurement of MAb Titer in Crude Cell Culture Samples, IBC Life Sciences: 26th International Antibody Development & Production, Bellevue, WA, by Susan Callahan and Richard Wu, Amgen, Inc.
January 2011 — A New High Throughput Micro-Chromatography Platform for Quantitative Analytical Sample Preparation WCBP, Washington, DC
September 2010 — A New Platform for High Throughput N-Glycan Sample Prep BioProcess International, Providence, RI
September 2010 — Rapid, High Throughput, High Sensitivity Determinations of MAb Concentration for Cell Line Screening and Process Optimization BioProcess International, Providence, RI
August 2010 — High Throughput Chromatographic Method Development on 5 µL Microcolumns Recovery of Biological Products XIV, Lake Tahoe, CA
April 2010 — Rapid Sample Prep for N-Glycan Analysis using High Throughput Micro Chromatography SBS Annual Conference and Exhibition, Phoenix, AZ. This poster is also available for viewing in the SBS 2010 Conference Poster Gallery »
January 2010 — A New Platform for High Throughput Micro Chromatography Analysis Well Characterized Biotechnology Pharmaceutical Symposium, Washington, DC
October 2009 — Rapid, Automated, High Precision Immunoassays for High Throughput Process Impurity Measurements BioProcess International, Raleigh, NC
October 2009 — High Throughput Chromatographic Method Development on 5 µL Microcolumns BioProcess International, Raleigh, NC
October 2009 — A New Approach to Rapid High Throughput Determinations of Product Concentration BioProcess International, Raleigh, NC
Articles
December 2011 — Fulton S, Murphy S, Reich J, Van Den Heuvel Z, Sakowski R, Smith R, Agee S. (2011) A High Throughput Microchromatography Platform for Quantitative Analytical Scale Protein Sample Preparation J Lab Autom 16:457—467.
January 15, 2011 — Overcoming Lab Automation Challenges: Flexibility Is Essential as There Is No Such Thing as One-Size-Fits-All Instrumentation GEN 31(2).
Technical Presentations
January 2011 — A New High Throughput Micro-Chromatography Platform for Quantitative Analytical Sample Prep LabAutomation 2011, Palm Springs, CA
October 2009 — Creating innovative tools to break through the critical bottlenecks of biomolecule analysis in biopharm manufacturing, biomarkers & life science research BioProcess International, Raleigh, NC
Press Releases
December 1, 2011 — Agilent Technologies Grows Life Sciences Business with Strategic Acquisitions in Next-Generation Sequencing and Automated Analytical Solutions for Pharma - Agilent Technologies signs acquisition agreement with BioSystem Development
July 19, 2011 — BioSystem Development closes a near $1 Million investment round
March 23, 2011 — BioSystem Development Honored as One of the 2011 “Wisconsin Companies to Watch”
March 18, 2011 — BioSystem Development Selected as a Top 300 Startup
January 31, 2011 — Agilent Technologies' AssayMAP Bravo and Cartridges for Protein Purification Provide an Automated Solution for High-Throughput Sample Preparation
December 14, 2010 — SLAS Names $10,000 Innovation Award Finalists for LabAutomation2011
December 8, 2010 — BioSystem Development and Agilent Technologies Collaborate to Bring Precision and High-Throughput to AssayMAP® Micro-scale Chromatography
November 3, 2010 — BioSystem Development and BAC BV Collaborate to Bring Industry-Leading Purification Ligands to High Throughput Biotherapeutic Process Development
October 11, 2010 — BioSystem Development closes a near $1 Million investment round
May 11, 2010 — BioSystem Development and ProZyme Join Forces to Revolutionize Glycan Sample Preparation
December 9, 2009 — BioSystem Development Launches its AssayMAP® MAb Titer Assay for Rapid, High-throughput Antibody Measurement in Bioprocess Samples
November 23, 2009 — BioSystem Development closes $1.4 Million investment round